– NSQIP database 2005-2016 (>800,000 patients) including open/laparoscopic cholecystectomies, ventral hernia repairs, and partial colectomies
– Comparing outcomes in emergent vs elective cases
– Primary outcome: aggregate of SSIs which includes wound disruption, superficial SSI, deep SSI, and organ space SSI
— ↑SSI in the emergency group (5.3% vs 3.6%)
— When controlling for multiple variables, emergency surgery associated with more SSIs (OR 1.15).
Paper 2: Lakhani et. al. (2022) Prophylactic negative pressure wound dressings reduces wound complications following emergency laparotomies: A systematic review and meta-analysis. Surgery
– NPWD remove excess fluid from subcutaneous space, ↓ collections/contaminants, promote angiogenesis, fibroblast infiltration
– Literature review 2005-2022 (NPWD, laparotomy, SSI)
– 1199 patients included (566 NPWD, 633 standard dressings)
— NPWD ↓ wound infection (OR 0.43) and wound breakdown (OR 0.36)
— No change in LOS, readmission
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